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ISMB
1993
13 years 8 months ago
Computationally Efficient Cluster Representation in Molecular Sequence Megaclassification
Molecular sequence megaclassification is a technique for automated protein sequence analysis and annotation. Implementation of the method has been limited by the need to store and...
David J. States, Nomi L. Harris, Lawrence Hunter
BMCBI
2010
103views more  BMCBI 2010»
13 years 7 months ago
MTRAP: Pairwise sequence alignment algorithm by a new measure based on transition probability between two consecutive pairs of r
Background: Sequence alignment is one of the most important techniques to analyze biological systems. It is also true that the alignment is not complete and we have to develop it ...
Toshihide Hara, Keiko Sato, Masanori Ohya
NAR
1998
161views more  NAR 1998»
13 years 6 months ago
Touring protein fold space with Dali/FSSP
The FSSP database and its new supplement, the Dali Domain Dictionary, present a continuously updated classification of all known 3D protein structures. The classification is deriv...
Liisa Holm, Chris Sander
BIBM
2008
IEEE
170views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
Protein Sequence Motif Super-Rule-Tree (SRT) Structure Constructed by Hybrid Hierarchical K-Means Clustering Algorithm
— Protein sequence motifs information is crucial to the analysis of biologically significant regions. The conserved regions have the potential to determine the role of the protei...
Bernard Chen, Jieyue He, Stephen Pellicer, Yi Pan
BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...