Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
We have elaborated a new method of recognizing protein coding sequences in genomic sequences. The method is exploiting a specific way of genetic code degeneration and relations bet...
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...