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» Cache-Oblivious Dynamic Programming for Bioinformatics
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APBC
2004
173views Bioinformatics» more  APBC 2004»
13 years 8 months ago
RNA Secondary Structure Prediction with Simple Pseudoknots
Pseudoknots are widely occurring structural motifs in RNA. Pseudoknots have been shown to be functionally important in different RNAs which play regulatory, catalytic, or structur...
Jitender S. Deogun, Ruben Donts, Olga Komina, Fang...
BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
14 years 1 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng
BIBM
2008
IEEE
112views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
Fast Alignments of Metabolic Networks
Network alignments are extensively used for comparing, exploring, and predicting biological networks. Existing alignment tools are mostly based on isomorphic and homeomorphic embe...
Qiong Cheng, Piotr Berman, Robert W. Harrison, Ale...
BIBE
2007
IEEE
128views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
QOMA2: Optimizing the alignment of many sequences
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Xu Zhang, Tamer Kahveci
VRML
2004
ACM
14 years 23 days ago
PathSim visualizer: an Information-Rich Virtual Environment framework for systems biology
Increasingly, biology researchers and medical practitioners are using computational tools to model and analyze dynamic systems across scales from the macro to the cellular to the ...
Nicholas F. Polys, Doug A. Bowman, Chris North, Re...