43190 search results - page 8565 / 8638 » Can Development Be Designed |
BMCBI
2008
13 years 10 months ago
2008
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
BMCBI
2007
13 years 10 months ago
2007
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
BMCBI
2007
13 years 10 months ago
2007
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
BMCBI
2008
13 years 10 months ago
2008
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
BMCBI
2008
13 years 10 months ago
2008
Background: Sequence searches are routinely employed to detect and annotate related proteins. However, a rapid growth of databases necessitates a frequent repetition of sequence s...