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» Can we Find Molecular Signatures from Gene Expression Data
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JCB
2006
129views more  JCB 2006»
13 years 8 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes
IWCIA
2009
Springer
14 years 3 months ago
Signatures of Combinatorial Maps
Abstract. In this paper, we address the problem of computing a canonical representation of an n-dimensional combinatorial map. To do so, we define two combinatorial map signatures...
Stéphane Gosselin, Guillaume Damiand, Chris...
BMCBI
2004
131views more  BMCBI 2004»
13 years 8 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
BMCBI
2007
115views more  BMCBI 2007»
13 years 8 months ago
SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis
Background: There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often sp...
Ari B. Kahn, Michael C. Ryan, Hongfang Liu, Barry ...
PRL
2006
130views more  PRL 2006»
13 years 8 months ago
Efficient huge-scale feature selection with speciated genetic algorithm
With increasing interest in bioinformatics, sophisticated tools are required to efficiently analyze gene information. The classification of gene expression profiles is crucial in ...
Jin-Hyuk Hong, Sung-Bae Cho