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» Can we Find Molecular Signatures from Gene Expression Data
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BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
APBC
2004
122views Bioinformatics» more  APBC 2004»
13 years 9 months ago
Evolution of Relative Synonymous Codon Usage in Human Immunodeficiency Virus Type 1
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
Peter L. Meintjes, Allen G. Rodrigo
PODS
2007
ACM
142views Database» more  PODS 2007»
14 years 7 months ago
Quasi-inverses of schema mappings
Schema mappings are high-level specifications that describe the relationship between two database schemas. Two operators on schema mappings, namely the composition operator and th...
Ronald Fagin, Phokion G. Kolaitis, Lucian Popa, Wa...
BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
KDD
2008
ACM
181views Data Mining» more  KDD 2008»
14 years 7 months ago
Fastanova: an efficient algorithm for genome-wide association study
Studying the association between quantitative phenotype (such as height or weight) and single nucleotide polymorphisms (SNPs) is an important problem in biology. To understand und...
Xiang Zhang, Fei Zou, Wei Wang 0010