Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
The genetical genomics approach has been used to study the genetic basis of variation in gene expression, where putative transcriptional regulators of genes are identified via gene...
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...