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» Can we Find Molecular Signatures from Gene Expression Data
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BMCBI
2006
179views more  BMCBI 2006»
13 years 8 months ago
Accurate and unambiguous tag-to-gene mapping in serial analysis of gene expression
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
Rodrigo Malig, Cristian Varela, Eduardo Agosin, Fr...
BMCBI
2004
181views more  BMCBI 2004»
13 years 8 months ago
Iterative class discovery and feature selection using Minimal Spanning Trees
Background: Clustering is one of the most commonly used methods for discovering hidden structure in microarray gene expression data. Most current methods for clustering samples ar...
Sudhir Varma, Richard Simon
BMCBI
2008
94views more  BMCBI 2008»
13 years 9 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...
CSB
2005
IEEE
143views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Multivariate gene selection: Does it help
When building predictors of disease state based on gene expression data, gene selection is performed in order to achieve a good performance and to identify a relevant subset of ge...
Carmen Lai, Marcel J. T. Reinders
BMCBI
2011
13 years 3 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso