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    BMCBI
    2010
    153views more  BMCBI 2010»
    Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
    13 years 10 months ago
    Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
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    Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
    Eva Freyhult, Mattias Landfors, Jenny Önskog,...
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    BMCBI
    2010
    89views more  BMCBI 2010»
    Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
    13 years 10 months ago
    Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study
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    Background: Tissue MicroArray technology aims to perform immunohistochemical staining on hundreds of different tissue samples simultaneously. It allows faster analysis, considerab...
    Federica Viti, Ivan Merelli, Mieke Timmermans, Mic...
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    BMCBI
    2007
    88views more  BMCBI 2007»
    Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
    13 years 10 months ago
    Use of DNA melting simulation software for in silico diagnostic assay design: targeting regions with complex melting curves and
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    Background: DNA melting curve analysis using double-stranded DNA-specific dyes such as SYTO9 produce complex and reproducible melting profiles, resulting in the detection of multi...
    John P. Rasmussen, Christopher P. Saint, Paul T. M...
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    BMCBI
    2008
    136views more  BMCBI 2008»
    GPAT: Retrieval of genomic annotation from large genomic position datasets
    13 years 10 months ago
    GPAT: Retrieval of genomic annotation from large genomic position datasets
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    Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
    Arnaud Krebs, Mattia Frontini, Làszlò...
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    BMCBI
    2008
    115views more  BMCBI 2008»
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
    13 years 10 months ago
    Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
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    Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
    Sudhakar Jonnalagadda, Rajagopalan Srinivasan
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