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ALMOB
2006
109views more  ALMOB 2006»
13 years 11 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2006
174views more  BMCBI 2006»
13 years 11 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
BMCBI
2006
128views more  BMCBI 2006»
13 years 11 months ago
Construction of a nasopharyngeal carcinoma 2D/MS repository with Open Source XML Database - Xindice
Background: Many proteomics initiatives require integration of all information with uniformcriteria from collection of samples and data display to publication of experimental resu...
Feng Li, Maoyu Li, Zhiqiang Xiao, Pengfei Zhang, J...
BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
BMCBI
2006
114views more  BMCBI 2006»
13 years 11 months ago
Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle
Background: AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply. An investig...
Qingfeng Chen, Yi-Ping Phoebe Chen