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BMCBI
2007
136views more  BMCBI 2007»
13 years 10 months ago
Reduced modeling of signal transduction - a modular approach
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
Markus Koschorreck, Holger Conzelmann, Sybille Ebe...
BMCBI
2008
116views more  BMCBI 2008»
13 years 10 months ago
A novel representation of RNA secondary structure based on element-contact graphs
Background: Depending on their specific structures, noncoding RNAs (ncRNAs) play important roles in many biological processes. Interest in developing new topological indices based...
Wenjie Shu, Xiaochen Bo, Zhiqiang Zheng, Shengqi W...
BMCBI
2008
128views more  BMCBI 2008»
13 years 10 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2010
126views more  BMCBI 2010»
13 years 10 months ago
GeneBrowser 2: an application to explore and identify common biological traits in a set of genes
Background: The development of high-throughput laboratory techniques created a demand for computer-assisted result analysis tools. Many of these techniques return lists of genes w...
Joel Arrais, João Fernandes, João Pe...
BMCBI
2010
113views more  BMCBI 2010»
13 years 10 months ago
Class prediction for high-dimensional class-imbalanced data
Background: The goal of class prediction studies is to develop rules to accurately predict the class membership of new samples. The rules are derived using the values of the varia...
Rok Blagus, Lara Lusa
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