5692 search results - page 1096 / 1139 » Challenges and Unsolved Problems |
BMCBI
2007
2007
Application of amino acid occurrence for discriminating different folding types of globular proteins
13 years 10 months ago
Background: Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology. The discrimination of ...
BMCBI
2007
13 years 10 months ago
2007
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
BMCBI
2008
13 years 10 months ago
2008
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
BMCBI
2008
13 years 10 months ago
2008
Background: Identification of approximate tandem repeats is an important task of broad significance and still remains a challenging problem of computational genomics. Often there ...
BMCBI
2008
13 years 10 months ago
2008
Background: The prediction of conformational B-cell epitopes is one of the most important goals in immunoinformatics. The solution to this problem, even if approximate, would help...