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13 years 8 months ago
Genes, Themes, and Microarrays: Using Information Retrieval for Large-Scale Gene Analysis
The immensevolumeof data resulting from DNAmicroarray experiments, accompaniedby an increase in the numberof publications discussing gene-related discoveries, presents a majordata...
Hagit Shatkay, Stephen Edwards, W. John Wilbur, Ma...
JCB
2007
198views more  JCB 2007»
13 years 6 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
CIBB
2008
13 years 8 months ago
Curating a Large-Scale Regulatory Network by Evaluating Its Consistency with Expression Datasets
Abstract. The analysis of large-scale regulatory models using data issued from genome-scale high-throughput experimental techniques is an actual challenge in the systems biology fi...
Carito Guziolowski, Jeremy Gruel, Ovidiu Radulescu...
BMCBI
2007
114views more  BMCBI 2007»
13 years 6 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...