3241 search results - page 636 / 649 » Challenges for Dataset Search |
ALMOB
2006
13 years 10 months ago
2006
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
BMCBI
2006
13 years 10 months ago
2006
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
BMCBI
2006
13 years 10 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
BMCBI
2007
13 years 9 months ago
2007
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
BMCBI
2007
13 years 9 months ago
2007
Background: Recent advances in Web and information technologies with the increasing decentralization of organizational structures have resulted in massive amounts of information r...