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» Challenges of sequencing human genomes
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BIBE
2005
IEEE
107views Bioinformatics» more  BIBE 2005»
14 years 2 months ago
DSIM: A Distance-Based Indexing Method for Genomic Sequences
In this paper, we propose a Distance-based Sequence Indexing Method (DSIM) for indexing and searching genome databases. Borrowing the idea of video compression, we compress the ge...
Xia Cao, Beng Chin Ooi, HweeHwa Pang, Kian-Lee Tan...
BMCBI
2007
147views more  BMCBI 2007»
13 years 9 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
BMCBI
2004
136views more  BMCBI 2004»
13 years 8 months ago
A SNP-centric database for the investigation of the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are an increasingly important tool for genetic and biomedical research. Although current genomic databases contain information o...
Alberto Riva, Isaac S. Kohane
CIKM
2009
Springer
14 years 23 days ago
Suffix trees for very large genomic sequences
A suffix tree is a fundamental data structure for string searching algorithms. Unfortunately, when it comes to the use of suffix trees in real-life applications, the current metho...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
BMCBI
2005
106views more  BMCBI 2005»
13 years 8 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...