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» Challenges of sequencing human genomes
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BMCBI
2011
13 years 13 days ago
PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus ge
Background: Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few...
Jiajie Zhang, Amir Madany Mamlouk, Thomas Martinet...
BMCBI
2006
92views more  BMCBI 2006»
13 years 9 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
NAR
2007
90views more  NAR 2007»
13 years 8 months ago
PigGIS: Pig Genomic Informatics System
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their hum...
Jue Ruan, Yiran Guo, Heng Li, Yafeng Hu, Fei Song,...
BMCBI
2007
78views more  BMCBI 2007»
13 years 8 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
BMCBI
2004
119views more  BMCBI 2004»
13 years 8 months ago
Identification of polymorphic tandem repeats by direct comparison of genome sequence from different bacterial strains : a web-ba
Background: Polymorphic tandem repeat typing is a new generic technology which has been proved to be very efficient for bacterial pathogens such as B. anthracis, M. tuberculosis, ...
France Denoeud, Gilles Vergnaud