Background: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA ...
Christian Rohde, Yingying Zhang, Richard Reinhardt...
Given a collection of contigs and mate-pairs. The Contig Scaffolding Problem is to order and orientate the given contigs in a manner that is consistent with as many mate-pairs as p...
It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. This paper presents a number of a...
: Despite many years of research on how to properly align sequences in the presence of sequencing errors, alternative splicing and micro-exons, the correct alignment of mRNA sequen...
Discovery of molecular markers for efficient identification of living organisms remains a challenge of high interest. The diversity of species can now be observed in details with ...
Pierre Peterlongo, Jacques Nicolas, Dominique Lave...