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» Challenges of sequencing human genomes
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CSB
2003
IEEE
14 years 2 months ago
A New Approach for Gene Annotation Using Unambiguous Sequence Joining
The problem addressed by this paper is accurate and automatic gene annotation following precise identification/annotation of exon and intron boundaries of biologically verified ...
Alexandre Tchourbanov, Daniel Quest, Hesham H. Ali...
BMCBI
2008
111views more  BMCBI 2008»
13 years 9 months ago
VisualRepbase: an interface for the study of occurrences of transposable element families
Background: Repbase is a reference database of eukaryotic repetitive DNA, which includes prototypic sequences of repeats and basic information described in annotations. Repbase al...
Sébastien Tempel, Matthew Jurka, Jerzy Jurk...
BMCBI
2005
169views more  BMCBI 2005»
13 years 8 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
JCB
2008
81views more  JCB 2008»
13 years 8 months ago
Estimating the Ancestral Recombinations Graph (ARG) as Compatible Networks of SNP Patterns
Traditionally nonrecombinant genome, i.e., mtDNA or Y chromosome, has been used for phylogeography, notably for ease of analysis. The topology of the phylogeny structure in this c...
Laxmi Parida, Marta Melé, Francesc Calafell...
FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 6 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...