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» Challenges of sequencing human genomes
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NAR
1998
112views more  NAR 1998»
13 years 8 months ago
MITOMAP: a human mitochondrial genome database--1998 update
We have continued to develop MITOMAP (http://www.gen.emory.edu/MITOMAP ), a comprehensive database for the human mitochondrial DNA (mtDNA). MITOMAP uses the mtDNA sequence as the ...
Andreas M. Kogelnik, Marie T. Lott, Michael D. Bro...
IPPS
2002
IEEE
14 years 1 months ago
Aligning Two Fragmented Sequences
Upon completion of the human and mouse genome sequences, world-wide sequencing capacity will turn to other complex organisms. Current strategies call for many of these genomes to ...
Vamsi Veeramachaneni, Piotr Berman, Webb Miller
CIDR
2009
180views Algorithms» more  CIDR 2009»
13 years 10 months ago
Data Management for High-Throughput Genomics
Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are fa...
Uwe Röhm, José A. Blakeley
SAC
2010
ACM
13 years 9 months ago
FANGS: high speed sequence mapping for next generation sequencers
Next Generation Sequencing machines are generating millions of short DNA sequences (reads) everyday. There is a need for efficient algorithms to map these sequences to the referen...
Sanchit Misra, Ramanathan Narayanan, Simon Lin, Al...
BMCBI
2007
110views more  BMCBI 2007»
13 years 8 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...