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» Challenges of sequencing human genomes
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KDD
2008
ACM
243views Data Mining» more  KDD 2008»
14 years 8 months ago
Permu-pattern: discovery of mutable permutation patterns with proximity constraint
Pattern discovery in sequences is an important problem in many applications, especially in computational biology and text mining. However, due to the noisy nature of data, the tra...
Meng Hu, Jiong Yang, Wei Su
ANOR
2010
125views more  ANOR 2010»
13 years 7 months ago
A Bayesian approach for the alignment of high-resolution NMR spectra
: The rapid progresses in human genome project and biotechnologies result in the sheer volume of datasets associated with in-depth scientific knowledge. Metabolomics is defined as ...
Seoung Bum Kim, Zhou Wang, Basavaraj Hiremath
BMCBI
2006
109views more  BMCBI 2006»
13 years 7 months ago
An integrated system for genetic analysis
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing a...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md...
BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis
Background: There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often sp...
Ari B. Kahn, Michael C. Ryan, Hongfang Liu, Barry ...