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» Challenges of sequencing human genomes
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BMCBI
2006
136views more  BMCBI 2006»
13 years 7 months ago
Java GUI for InterProScan (JIPS): A tool to help process multiple InterProScans and perform ortholog analysis
Background: Recent, rapid growth in the quantity of available genomic data has generated many protein sequences that are not yet biochemically classified. Thus, the prediction of ...
Aijazuddin Syed, Chris Upton
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...
MM
2006
ACM
178views Multimedia» more  MM 2006»
14 years 1 months ago
Multimedia signal processing for behavioral quantification in neuroscience
While there have been great advances in quantification of the genotype of organisms, including full genomes for many species, the quantification of phenotype is at a comparatively...
Peter Andrews, Haibin Wang, Dan Valente, Jih&egrav...
NN
2006
Springer
13 years 7 months ago
Self-organizing neural networks to support the discovery of DNA-binding motifs
Identification of the short DNA sequence motifs that serve as binding targets for transcription factors is an important challenge in bioinformatics. Unsupervised techniques from t...
Shaun Mahony, Panayiotis V. Benos, Terry J. Smith,...