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» Challenges of sequencing human genomes
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RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
KDD
2001
ACM
163views Data Mining» more  KDD 2001»
14 years 8 months ago
Learning to recognize brain specific proteins based on low-level features from on-line prediction servers
During the last decade, the area of bioinformatics has produced an overwhelming amount of data, with the recently published draft of the human genome being the most prominent exam...
Henrik Boström, Joakim Cöster, Lars Aske...
BMCBI
2002
126views more  BMCBI 2002»
13 years 7 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
BMCBI
2008
323views more  BMCBI 2008»
13 years 7 months ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
CVPR
1998
IEEE
14 years 9 months ago
Tracking People with Twists and Exponential Maps
This paper demonstrates a new visual motion estimation technique that is able to recover high degree-of-freedom articulated human body configurations in complex video sequences. W...
Christoph Bregler, Jitendra Malik