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» Challenges of sequencing human genomes
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BMCBI
2011
12 years 11 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
JBI
2002
126views Bioinformatics» more  JBI 2002»
13 years 7 months ago
Characteristic attributes in cancer microarrays
Rapid advances in genome sequencing and gene expression microarray technologies are providing unprecedented opportunities to identify specific genes involved in complex biological...
Indra Neil Sarkar, Paul J. Planet, T. E. Bael, S. ...
ISBI
2011
IEEE
12 years 11 months ago
Automated lineage tree reconstruction from Caenorhabditis elegans image data using particle filtering based cell tracking
Caenorhabditis elegans is an important model organism for the study of molecular mechanisms of development and disease processes, due to its well-known genome and invariant cell l...
Noemí Carranza-Herrezuelo, Ihor Smal, Oleh ...
FUZZIEEE
2007
IEEE
14 years 1 months ago
Mining and Predicting CpG islands
— A DNA sequence can be described as a string composed of four symbols: A, T, C and G. Each symbol represents a chemically distinct nucleotide molecule. Combinations of two nucle...
Christopher Previti, Oscar Harari, Coral del Val
BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...