524 search results - page 8 / 105 » Challenges of sequencing human genomes |
BMCBI
2006
13 years 8 months ago
2006
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
FSTTCS
2003
Springer
14 years 2 months ago
2003
Springer
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
BMCBI
2010
13 years 3 months ago
2010
Background -: The availability of multiple whole genome sequences has facilitated in silico identification of fixed and polymorphic transposable elements (TE). Whereas polymorphic...
BMCBI
2008
13 years 9 months ago
2008
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
RECOMB
2006
Springer
14 years 9 months ago
2006
Springer
Inferring orthologous and paralogous genes is an important problem in whole genomes comparisons, both for functional or evolutionary studies. In this paper, we introduce a new appr...