Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
This paper integrates the signal, context and structure features for genome-wide promoter recognition, which is critical in many DNA sequence analysis tasks. First, CpG islands ar...
Gene duplications are scattered widely throughout the human genome. A single-base difference located in nearly identical duplicated segments may be misjudged as a single nucleotid...
Chromosomal aberrations are differences in DNA sequence copy number of chromosome regions 3 . These differences may be crucial genetic events in the development and progression o...
Kees Jong, Elena Marchiori, Aad van der Vaart, Bau...
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...