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BMCBI
2010
106views more  BMCBI 2010»
13 years 9 months ago
TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays
Background: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, ...
Henrik Bengtsson, Pierre Neuvial, Terence P. Speed
BMCBI
2008
174views more  BMCBI 2008»
13 years 9 months ago
Evolutionary approaches for the reverse-engineering of gene regulatory networks: A study on a biologically realistic dataset
Background: Inferring gene regulatory networks from data requires the development of algorithms devoted to structure extraction. When only static data are available, gene interact...
Cédric Auliac, Vincent Frouin, Xavier Gidro...
BMCBI
2007
89views more  BMCBI 2007»
13 years 9 months ago
msmsEval: tandem mass spectral quality assignment for high-throughput proteomics
Background: In proteomics experiments, database-search programs are the method of choice for protein identification from tandem mass spectra. As amino acid sequence databases grow...
Jason W. H. Wong, Matthew J. Sullivan, Hugh M. Car...
BMCBI
2007
112views more  BMCBI 2007»
13 years 9 months ago
AUG_hairpin: prediction of a downstream secondary structure influencing the recognition of a translation start site
Background: The translation start site plays an important role in the control of translation efficiency of eukaryotic mRNAs. The recognition of the start AUG codon by eukaryotic r...
Alexey V. Kochetov, Andrey Palyanov, Igor I. Titov...
BMCBI
2010
132views more  BMCBI 2010»
13 years 9 months ago
Data structures and compression algorithms for high-throughput sequencing technologies
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...