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BMCBI
2007
107views more  BMCBI 2007»
13 years 9 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
BMCBI
2008
114views more  BMCBI 2008»
13 years 9 months ago
Identifying a few foot-and-mouth disease virus signature nucleotide strings for computational genotyping
Background: Serotypes of the Foot-and-Mouth disease viruses (FMDVs) were generally determined by biological experiments. The computational genotyping is not well studied even with...
Guohui Lin, Zhipeng Cai, Junfeng Wu, Xiu-Feng Wan,...
BMCBI
2007
175views more  BMCBI 2007»
13 years 9 months ago
Fast automated cell phenotype image classification
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
Nicholas A. Hamilton, Radosav S. Pantelic, Kelly H...
BMCBI
2007
130views more  BMCBI 2007»
13 years 9 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2008
228views more  BMCBI 2008»
13 years 9 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye