Expressed sequence tags (ESTs) have provided a first glimpse of the collection of transcribed sequences in a variety of organisms. However, a careful analysis of this sequence dat...
John Quackenbush, Feng Liang, Ingeborg Holt, Geo P...
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
To support non-trivial clients, such as data exploration and analysis environments, digital libraries must be able to describe the access modes that their contents support. We pre...
This paper presents an evaluation of the design decisions made in four state-of-the-art constraint solvers; Choco, ECLiPSe, Gecode, and Minion. To assess the impact of design deci...