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BMCBI
2010
227views more  BMCBI 2010»
13 years 7 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
ICML
2005
IEEE
14 years 8 months ago
Large scale genomic sequence SVM classifiers
In genomic sequence analysis tasks like splice site recognition or promoter identification, large amounts of training sequences are available, and indeed needed to achieve suffici...
Bernhard Schölkopf, Gunnar Rätsch, S&oum...
BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
BMCBI
2007
178views more  BMCBI 2007»
13 years 7 months ago
SVM clustering
Background: Support Vector Machines (SVMs) provide a powerful method for classification (supervised learning). Use of SVMs for clustering (unsupervised learning) is now being cons...
Stephen Winters-Hilt, Sam Merat