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» Cloud computing for comparative genomics
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VEE
2012
ACM
232views Virtualization» more  VEE 2012»
12 years 6 months ago
DVM: towards a datacenter-scale virtual machine
As cloud-based computation becomes increasingly important, providing a general computational interface to support datacenterscale programming has become an imperative research age...
Zhiqiang Ma, Zhonghua Sheng, Lin Gu, Liufei Wen, G...
BMCBI
2010
86views more  BMCBI 2010»
13 years 11 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
BMCBI
2008
79views more  BMCBI 2008»
13 years 11 months ago
A high-throughput pipeline for designing microarray-based pathogen diagnostic assays
Background: We present a methodology for high-throughput design of oligonucleotide fingerprints for microarray-based pathogen diagnostic assays. The oligonucleotide fingerprints, ...
Ravi Vijaya Satya, Nela Zavaljevski, Kamal Kumar, ...
BMCBI
2008
77views more  BMCBI 2008»
13 years 11 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2007
132views more  BMCBI 2007»
13 years 11 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen