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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
SCOWLP classification: Structural comparison and analysis of protein binding regions
Background: Detailed information about protein interactions is critical for our understanding of the principles governing protein recognition mechanisms. The structures of many pr...
Joan Teyra, Maciej Paszkowski-Rogacz, Gerd Anders,...
BMCBI
2008
154views more  BMCBI 2008»
13 years 7 months ago
GenomeMatcher: A graphical user interface for DNA sequence comparison
Background: The number of available genome sequences is increasing, and easy-to-use software that enables efficient comparative analysis is needed. Results: We developed GenomeMat...
Yoshiyuki Ohtsubo, Wakako Ikeda-Ohtsubo, Yuji Naga...
BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Ornithine decarboxylase antizyme finder (OAF): Fast and reliable detection of antizymes with frameshifts in mRNAs
Background: Ornithine decarboxylase antizymes are proteins which negatively regulate cellular polyamine levels via their affects on polyamine synthesis and cellular uptake. In vir...
Michaël Bekaert, Ivaylo P. Ivanov, John F. At...
BMCBI
2008
91views more  BMCBI 2008»
13 years 7 months ago
t2prhd: a tool to study the patterns of repeat evolution
Background: The models developed to characterize the evolution of multigene families (such as the birth-and-death and the concerted models) have also been applied on the level of ...
Botond Sipos, Kálmán Somogyi, Istv&a...