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» Clustered Sequence Representation for Fast Homology Search
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JCB
2007
106views more  JCB 2007»
13 years 7 months ago
Clustered Sequence Representation for Fast Homology Search
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
Michael Cameron, Yaniv Bernstein, Hugh E. Williams
APBC
2004
13 years 8 months ago
Variable-length Intervals in Homology Search
Fast, accurate, and scalable search techniques for homology searching of large genomic collections are becoming an increasingly important requirement as genomic sequence collectio...
Abhijit Chattaraj, Hugh E. Williams
CSB
2004
IEEE
142views Bioinformatics» more  CSB 2004»
13 years 11 months ago
FastR: Fast Database Search Tool for Non-Coding RNA
The discovery of novel non-coding RNAs has been among the most exciting recent developments in Biology. Yet, many more remain undiscovered. It has been hypothesized that there is ...
Vineet Bafna, Shaojie Zhang
BMCBI
2011
12 years 11 months ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
BMCBI
2010
101views more  BMCBI 2010»
13 years 7 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...