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» Clustering the annotation space of proteins
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NAR
2000
111views more  NAR 2000»
13 years 7 months ago
ProtoMap: automatic classification of protein sequences and hierarchy of protein families
The ProtoMap site offers an exhaustive classification of all proteins in the SWISS-PROT database, into groups of related proteins. The classification is based on analysis of all p...
Golan Yona, Nathan Linial, Michal Linial
BMCBI
2010
122views more  BMCBI 2010»
13 years 2 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
Discovering functional interaction patterns in protein-protein interaction networks
Background: In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of ge...
Mehmet E. Turanalp, Tolga Can
NAR
2011
257views Computer Vision» more  NAR 2011»
12 years 10 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
JBCB
2010
138views more  JBCB 2010»
13 years 2 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur