Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
Background: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic developme...
Bo Zhang, Beibei Chen, Tao Wu, Zhenyu Xuan, Xiaope...
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
Mark J. Alston, John Seers, Jay C. D. Hinton, Sach...