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» Coding Exon Detection Using Comparative Sequences
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RECOMB
2004
Springer
14 years 10 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
BMCBI
2006
111views more  BMCBI 2006»
13 years 9 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BIB
2006
172views more  BIB 2006»
13 years 9 months ago
Advances in the Exon-Intron Database (EID)
Investigation of exon^intron gene structures is a non-trivial task due to enormous expansions of the eukaryotic genomes, great variety of gene forms, and the imperfectness in sequ...
Valery Shepelev, Alexei Fedorov
CSB
2002
IEEE
121views Bioinformatics» more  CSB 2002»
14 years 2 months ago
Fast and Sensitive Algorithm for Aligning ESTs to Human Genome
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
Jun Ogasawara, Shinichi Morishita
CSB
2003
IEEE
14 years 3 months ago
A New Approach for Gene Annotation Using Unambiguous Sequence Joining
The problem addressed by this paper is accurate and automatic gene annotation following precise identification/annotation of exon and intron boundaries of biologically verified ...
Alexandre Tchourbanov, Daniel Quest, Hesham H. Ali...