858 search results - page 159 / 172 » Collection understanding |
BMCBI
2010
13 years 7 months ago
2010
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
BMCBI
2010
13 years 7 months ago
2010
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
BMCBI
2007
13 years 7 months ago
2007
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
BMCBI
2007
13 years 7 months ago
2007
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
BMCBI
2008
13 years 7 months ago
2008
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...