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» Combinations of Weak Classifiers
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BMCBI
2010
149views more  BMCBI 2010»
13 years 8 months ago
A multifactorial analysis of obesity as CVD risk factor: Use of neural network based methods in a nutrigenetics context
Background: Obesity is a multifactorial trait, which comprises an independent risk factor for cardiovascular disease (CVD). The aim of the current work is to study the complex eti...
Ioannis K. Valavanis, Stavroula G. Mougiakakou, Ke...
BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2006
143views more  BMCBI 2006»
13 years 8 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2007
119views more  BMCBI 2007»
13 years 8 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2005
160views more  BMCBI 2005»
13 years 8 months ago
Data-poor categorization and passage retrieval for Gene Ontology Annotation in Swiss-Prot
Background: In the context of the BioCreative competition, where training data were very sparse, we investigated two complementary tasks: 1) given a Swiss-Prot triplet, containing...
Frédéric Ehrler, Antoine Geissbü...