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» Combinatorial Problems on Strings with Applications to Prote...
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BMCBI
2006
122views more  BMCBI 2006»
13 years 7 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2007
137views more  BMCBI 2007»
13 years 7 months ago
Bayesian refinement of protein functional site matching
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
Kanti V. Mardia, Vysaul B. Nyirongo, Peter J. Gree...
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
IPPS
2005
IEEE
14 years 1 months ago
FROST: Revisited and Distributed
FROST (Fold Recognition-Oriented Search Tool) [6] is a software whose purpose is to assign a 3D structure to a protein sequence. It is based on a series of filters and uses a dat...
Vincent Poirriez, Rumen Andonov, Antoine Marin, Je...
BMCBI
2006
132views more  BMCBI 2006»
13 years 7 months ago
Length-dependent prediction of protein intrinsic disorder
Background: Due to the functional importance of intrinsically disordered proteins or protein regions, prediction of intrinsic protein disorder from amino acid sequence has become ...
Kang Peng, Predrag Radivojac, Slobodan Vucetic, A....