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BMCBI
2007
141views more  BMCBI 2007»
13 years 9 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
CASCADE: a novel quasi all paths-based network analysis algorithm for clustering biological interactions
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2007
101views more  BMCBI 2007»
13 years 9 months ago
Statistical validation of megavariate effects in ASCA
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
Daniel J. Vis, Johan A. Westerhuis, Age K. Smilde,...
BMCBI
2007
156views more  BMCBI 2007»
13 years 9 months ago
Accuracy of structure-based sequence alignment of automatic methods
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
Changhoon Kim, Byungkook Lee
BMCBI
2007
153views more  BMCBI 2007»
13 years 9 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
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