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BMCBI
2007
151views more  BMCBI 2007»
13 years 8 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
IJCAI
2007
13 years 9 months ago
Integration of Hybrid Bio-Ontologies using Bayesian Networks for Knowledge Discovery
This paper describes how high level biological knowledge obtained from ontologies such as the Gene Ontology (GO) can be integrated with low level information extracted from a Baye...
Kenneth McGarry, Sheila Garfield, Nick Morris, Ste...
ER
2007
Springer
187views Database» more  ER 2007»
14 years 2 months ago
Metamodeling Integration Architecture for Open Biomedical Ontologies: The GO Extensions' Case Study
New technologies used in biology are generating huge quantities of data; up to two petabytes of overall data are to be expected by the end of the decade. Modern biology also has t...
Marie-Noëlle Terrasse, Marinette Savonnet, Er...
BMCBI
2010
214views more  BMCBI 2010»
13 years 8 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2005
106views more  BMCBI 2005»
13 years 7 months ago
Thesaurus-based disambiguation of gene symbols
Background: Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge. However, disambiguation of gene s...
Bob J. A. Schijvenaars, Barend Mons, Marc Weeber, ...