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BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
BMCBI
2010
165views more  BMCBI 2010»
13 years 7 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2008
162views more  BMCBI 2008»
13 years 7 months ago
Background correction using dinucleotide affinities improves the performance of GCRMA
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...