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» Combining microarrays and genetic analysis
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BMCBI
2011
13 years 4 months ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch
BMCBI
2010
96views more  BMCBI 2010»
13 years 10 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2008
158views more  BMCBI 2008»
13 years 10 months ago
Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent compo
Background: The analysis of high-throughput gene expression data sets derived from microarray experiments still is a field of extensive investigation. Although new approaches and ...
Dominik Lutter, Peter Ugocsai, Margot Grandl, Evel...
BMCBI
2008
151views more  BMCBI 2008»
13 years 10 months ago
Application of the Linux cluster for exhaustive window haplotype analysis using the FBAT and Unphased programs
Background: Genetic association studies have been used to map disease-causing genes. A newly introduced statistical method, called exhaustive haplotype association study, analyzes...
Hiroyuki Mishima, Andrew C. Lidral, Jun Ni
BMCBI
2010
124views more  BMCBI 2010»
13 years 10 months ago
GPFrontend and GPGraphics: graphical analysis tools for genetic association studies
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel,...