Global constraints are used in constraint programming to help users specify patterns that occur frequently in the real world. In addition, global constraints facilitate the use of ...
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Hard real-time embedded distributed systems pose huge demands in their implementation which must contain as few faults as possible. Over the past years, model-driven development a...
WE practices lack an impact on industry, partly due to a WE field that is not quality-aware. In fact, it is difficult to find WE methodologies that pay explicit attention to qualit...
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...