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BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi
BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
Prodigal: prokaryotic gene recognition and translation initiation site identification
Background: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the num...
Doug Hyatt, Gwo-Liang Chen, Philip F. LoCascio, Mi...
BMCBI
2006
74views more  BMCBI 2006»
13 years 7 months ago
An unsupervised classification scheme for improving predictions of prokaryotic TIS
Background: Although it is not difficult for state-of-the-art gene finders to identify coding regions in prokaryotic genomes, exact prediction of the corresponding translation ini...
Maike Tech, Peter Meinicke
BMCBI
2006
207views more  BMCBI 2006»
13 years 7 months ago
A new measure for functional similarity of gene products based on Gene Ontology
Background: Gene Ontology (GO) is a standard vocabulary of functional terms and allows for coherent annotation of gene products. These annotations provide a basis for new methods ...
Andreas Schlicker, Francisco S. Domingues, Jö...
BMCBI
2010
155views more  BMCBI 2010»
13 years 7 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...