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» Comparative evaluation of gene-set analysis methods
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400views
13 years 2 months ago
Partitioning Histopathological Images: An Integrated Framework for Supervised Color-Texture Segmentation and Cell Splitting
For quantitative analysis of histopathological images, such as the lymphoma grading systems, quantification of features is usually carried out on single cells before categorizing...
Hui Kong, Metin Gurcan, and Kamel Belkacem-Boussai...
JCB
2002
116views more  JCB 2002»
13 years 7 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
BMCBI
2010
155views more  BMCBI 2010»
13 years 4 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
CIKM
2007
Springer
14 years 1 months ago
Regularized locality preserving indexing via spectral regression
We consider the problem of document indexing and representation. Recently, Locality Preserving Indexing (LPI) was proposed for learning a compact document subspace. Different from...
Deng Cai, Xiaofei He, Wei Vivian Zhang, Jiawei Han