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BMCBI
2010
123views more  BMCBI 2010»
13 years 10 months ago
eGIFT: Mining Gene Information from the Literature
Background: With the biomedical literature continually expanding, searching PubMed for information about specific genes becomes increasingly difficult. Not only can thousands of r...
Catalina O. Tudor, Carl J. Schmidt, K. Vijay-Shank...
BMCBI
2008
128views more  BMCBI 2008»
13 years 10 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
BMCBI
2007
104views more  BMCBI 2007»
13 years 10 months ago
Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation
Background: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main...
Marija Cvijovic, Daniel Dalevi, Elizabeth Bilsland...
BMCBI
2010
101views more  BMCBI 2010»
13 years 10 months ago
Hidden Markov model speed heuristic and iterative HMM search procedure
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
L. Steven Johnson, Sean R. Eddy, Elon Portugaly
BMCBI
2007
157views more  BMCBI 2007»
13 years 10 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
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