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BMCBI
2008
13 years 10 months ago
2008
Background: There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not account f...
BMCBI
2007
13 years 10 months ago
2007
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
BMCBI
2006
13 years 9 months ago
2006
Background: Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of the Mic...
BMCBI
2006
13 years 9 months ago
2006
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
BMCBI
2006
13 years 9 months ago
2006
Background: The German cDNA Consortium has been cloning full length cDNAs and continued with their exploitation in protein localization experiments and cellular assays. However, t...