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BMCBI
2007
132views more  BMCBI 2007»
13 years 9 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
BMCBI
2007
148views more  BMCBI 2007»
13 years 9 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2007
101views more  BMCBI 2007»
13 years 9 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
ESE
2006
154views Database» more  ESE 2006»
13 years 9 months ago
Prioritizing JUnit Test Cases: An Empirical Assessment and Cost-Benefits Analysis
Test case prioritization provides a way to run test cases with the highest priority earliest. Numerous empirical studies have shown that prioritization can improve a test suite�...
Hyunsook Do, Gregg Rothermel, Alex Kinneer
BMCBI
2007
99views more  BMCBI 2007»
13 years 9 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi