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BMCBI
2005
118views more  BMCBI 2005»
13 years 7 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
NAR
2006
120views more  NAR 2006»
13 years 7 months ago
TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
Blaise T. F. Alako, Daphne Rainey, Harm Nijveen, J...
BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
PoGO: Prediction of Gene Ontology terms for fungal proteins
Background: Automated protein function prediction methods are the only practical approach for assigning functions to genes obtained from model organisms. Many of the previously re...
Jaehee Jung, Gangman Yi, Serenella A. Sukno, Micha...
BMCBI
2002
76views more  BMCBI 2002»
13 years 7 months ago
The SGS3 protein involved in PTGS finds a family
Background: Post transcriptional gene silencing (PTGS) is a recently discovered phenomenon that is an area of intense research interest. Components of the PTGS machinery are being...
Alex Bateman
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...