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BMCBI
2008
112views more  BMCBI 2008»
13 years 8 months ago
GlycomeDB - integration of open-access carbohydrate structure databases
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
René Ranzinger, Stephan Herget, Thomas Wett...
BMCBI
2008
109views more  BMCBI 2008»
13 years 8 months ago
LTRharvest, an efficient and flexible software for de novo detection of LTR retrotransposons
Background: Transposable elements are abundant in eukaryotic genomes and it is believed that they have a significant impact on the evolution of gene and chromosome structure. Whil...
David Ellinghaus, Stefan Kurtz, Ute Willhoeft
BMCBI
2008
116views more  BMCBI 2008»
13 years 8 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Statistical significance of quantitative PCR
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
Yann Karlen, Alan McNair, Sébastien Persegu...
BMCBI
2008
128views more  BMCBI 2008»
13 years 8 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...